As the Karen Hughes approved story goes, Bush found Jesus in 1986, was born again, and thus everything before that is irrelevant. It's rather similiar to 9/11. You know, "being born again changed everything." "9/11 changed everything." Both provide a way for Bush to not actually take responsibility for anything he did before those moments.
If the Kelley/Sharon Bush allegations are true, then Bush was snorting coke in Camp David after he supposedly turned his life around with the help of religion. And, just because Sharon Bush is a wee bit pissed off that her former husband, the president's brother, got herpes from whores in Asia, is no reason to discount what she says...